no, it's not the same. When you are playing Coach pick from depth chart, you coach try to play with the best players that you have and when you set up Strictly follow Depth Chart, you coach use just the 5 starting players.But sometimes, if the players have a low stamina or make fouls, even in Strictly follow Depth Chart, you coach will change those players with ,,fresh ones'' from reserves.
Also, if you are winning with more than 20 points, in the last quarter, you coach will put in game the reserves players, taking off from court you starting 5 players.