If you know that the best scorer is the opponent SF you should play man-to-man putting your best defender on SF (defensive position, at least).
I like Box & one and I think that this is the best solution against iso-offense.
As I understood, the "one" is the best defender that goes on the best opponent scorer. Of course inside/outside means that you expect the opponent plays inside/outside offense.
Not sure at 100% but I think that you have to put your best defender on SF (defensive position).