IF you want to prioritize training, you could aim for a 6-man rotation with 1on1 for forwards.
Select (up to) 8 players for each game, ON SF- and PF-positions you set 2 of your TO:s to starter, backup and reserve. The other positions have one player as starter and a second player as backup and reserve.
You must select "Strictly Follow Depth Chart".
By doing this, you maximize your chance of getting 48min on your TO:s. No guarantee thou, they could foul out/injure them selfs. Coach can even yank them in a blowout or when he feels like it =) But usually it works out fine.
You could let your best TO:s(preferably PG,SG or C) double as a backup+reserve in another game, utilizing his skills in more than one game a week.
If you do this, you probably need a Center that do not require training, to start your leaguegames at C-spot for you, with your (two best inside)TO:s as backup+reserve in one game each.
Optimal/Minimal roster: 2 starting Guards, 1 starting C, 6 TO:s (4 who can double as backup guards, 2 as backup C), 2 backup guards and 1 C for cup/scrimmages(all play 48min). Total: 12 players.
Happy training!