IMO, this is really a decision for managers to make. We designed the game engine so that, like with every other comparison, it is the relative skills that matter. I think you have probably noticed by now that against, say, a player with tremendous inside scoring, the difference between atrocious and respectable inside defense is actually not that great, because the inside scorer is going to be dominant in all of these cases. It is for this same reason that, against a tremendous inside scorer, you shouldn't expect that an improvement in shot blocking from atrocious to respectable will have a major impact. Against a respectable inside scorer, it will have a much larger impact.