Yup, even in the real world, a team with all-world centers won't do much if the team can't get the ball up the court or get an inbound pass to the big guys.
The Forum chatter these days is a lot about the high value that guards now have, since they are harder to train, cost more on the TL, and seem to control the outcome of games to somewhat greater degree than the big men. There was one strategy in particular (related to understanding the importance of game flow) that I saw a few teams employing this season that resulted in these teams just playing way over their heads. Two of my surprising losses came against teams doing this (and most of my losses are not surprising since I know where I stand...) I've tried it out a few times now and either the dice are just rolling my way or it really helps. I won't mention what this strategy is, especially since I don't know if these teams fully understood what they did, but it was a revelation to me and I've shifted my course ever so slightly to help my team take full advantage for next season.
And sometimes dumb luck does factor into these games. I think my team has had it's share of jaw-dropping bad losses this season, so I feel for TWSS.
Don't ask what sort of Chunks they are, you probably don't want to know. Blowing Chunks since Season 4!