Another factor I think is tactics, for example I believe a center will get better player ratings playing Look Inside / 2-3 than in a Run and Gun / 1-3-1 game.
I think this may depend on the players skills. if you have a center who is pretty monoskilled aka high RB+ID+IS+SB he get better ratings with inside focused tactics as you said, but if you have a relatively multiskilled center with some JR+JS he might get a better rating with RnG.