I think there are always going to be important matchups when you don't want them, whether those are within your division or not.
In my opinion the likelyhood of an important match-up is bigger conferential.
The interconferential games seem less attractive to me in terms of play-offs and relegation, so it seems a good thing they get scheduled together with an attractive cup-run.
The point is that right now, it's the same matchups at roughly the same time, season after season.
Although thinking about it further, I do think that the calendar should be fixed slightly. The final game of the season should be the previous season's divisonal 1 vs 2, 3 vs 4, etc... since those matchups have the greatest likelihood of being directly relevant to playoffs, relegation, etc.
--> Seems a good suggestion but this way, the matchups will be scheduled even more tightly.
About the same matchups: every season your own conference gets fresh teams so there will always be some variation. The progress a team can make within a year because of training etc, is at the moment pretty large. So it doesn't bother me yet.
Climbing the BB-mountain. Destination: the top.