If you have a look at previous season's draft's, you will find that in the first round, most people get their 1st, 2nd or 3rd preference.
So in terms of getting one of your top 3 preferences in the first round, its nearly a given, regardless of when you pick in the first round.
In terms of being guaranteed to pick one of the best 3 players in the draft though, that would require you to scout and interview everyone in the draft, which is basically 3 x 48 = 146 scouting points. That would cost $730k dollars to get that many points for this season.
Points carry over from season to season, so if you really wanted to do this, you could do it over a few seasons. I don't recommend utilizing 146 points on the draft through.
In general, I think most people who spend their skill points wisely, and in a tactical manner, will spend about 35-40 points per draft, in order to get enough information out of the draft that their top 4 or 5 picks are well known to be of top quality.